Vylex Information

Active Ingredients:
- UC-II 40mg (Undenatured Type II Collagen)
- Aflapin 100mg (Boswellia serrata gum extract)
Novel active ingredients that support joint health by their disease-modifying anti-inflammatory & cartilage protecting pathways
Disease-modifying mechanism of action that have been evaluated through multiple pre-clinical studies
- Activates T regulatory (Treg) cells which increase the production of anti-inflammatory mediators such as IL-4, IL-10 & TGF-β, which in turn, stimulate chondrocytes to synthesize cartilage matrix components
- Inhibits production of cartilage degrading enzymes, matrix metalloproteinases MMP-3 & MMP-13, which prevents cartilage breakdown
- Reduce the production of pro-inflammatory mediators such as 5-lipooxygenase, IL-1β, TNF-α, IL-2 & IL-17
Clinical trials have shown efficacy & safety in osteoarthritis patients
- Pain relief from 5-7 days
- Pain relief vs glucosamine + chondroitin
- Improves flexibility & physical function
- Enhanced safety profile
Easy compliance 1 small capsule daily

Efficacy and Tolerability of an Undenatured Type II Collagen Supplement in Modulating Knee Osteoarthritis Symptoms: A Multicenter Randomized, Double-Blind, Placebo-Controlled Study – 2016
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Safety and Efficacy of Undenatured Type II Collagen in the Treatment of Osteoarthritis of the Knee: A Clinical Trial – 2009
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A Non-Interventional, Prospective, Multicentric Real Life Indian Study to Assess Safety and Effectiveness of Undenatured Type 2 Collagen in Management of Osteoarthritis – 2019
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A Double Blind, Randomized, Placebo Controlled Clinical Study Evaluates the Early Efficacy of Aflapin in Subjects with Osteoarthritis of Knee – 2011
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Efficacy and Tolerability of 5-Loxin and Aflapin Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study – 2010
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Clinical Trials Complete Set
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